Ji'Ayir Brown (born January 25, 2000) is an American football safety for the San Francisco 49ers of the National Football League (NFL). He played college football at Lackawanna and Penn State Nittany Lions.In 2020, Brown transferred to Penn State University. After spending his first year in 2020 as a backup, he took over as a starter in 2021. In 13 starts, he had 73 tackles, six interceptions and one touchdown.Ji'Ayir Brown returned to Penn State in 2022. He was named the defensive MVP of the 2023 Rose Bowl.